Dynamic characterization and hemodynamic effects of pulmonary waves in fetal lambs using cardiac extrasystoles and beat-by-beat wave intensity analysis
Joseph J Smolich, Jonathan P Mynard, Daniel J Penny
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology | AMER PHYSIOLOGICAL SOC | Published : 2009
Steady-state wave intensity (WI) analysis indicates that characteristic midsystolic falls in fetal pulmonary trunk (PT) and artery (PA) blood flow are due to an extremely large backward-running compression wave (BCW(ms)) that 1) originates from the pulmonary microvasculature by a combination of cyclical pulmonary vasoconstriction and vascular reflection of the forward-running compression wave (FCW(is)) associated with impulsive right ventricular ejection, and 2) is transmitted into the PT. However, no information is available about the dynamic properties of PA BCW(ms) and its contribution to beat-to-beat regulation of pulmonary hemodynamics. Accordingly, beat-by-beat WI analysis was performe..View full abstract
This work was supported by a Grant-in-Aid from the National Heart Foundation of Australia.