Probiotics for the treatment of eczema: a systematic review
RJ Boyle, FJ Bath-Hextall, J Leonardi-Bee, DF Murrell, ML-K Tang
CLINICAL AND EXPERIMENTAL ALLERGY | WILEY | Published : 2009
BACKGROUND: Probiotics have been proposed as a treatment for eczema, but the results of intervention trials have been mixed. OBJECTIVE: To evaluate the efficacy of probiotics for treating eczema by performing a systematic review of randomized-controlled trials (RCTs). DESIGN: We searched the Cochrane Skin Group Specialised Register, Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE, PsycINFO, AMED, LILACS, ISI Web of Science, the reference lists of articles, ongoing clinical trial registers and conference proceedings. RCTs of live orally ingested microorganisms for the treatment of eczema were eligible for inclusion. RESULTS: Twelve trials (781 participants) were identified. Me..View full abstract
Sources of support: M. L.-K. T. was supported by a Murdoch Children's Research Institute Salary Grant. Robert Boyle was supported by a University of Melbourne Baillieu Scholarship, a Murdoch Children's Research Institute Postgraduate Scholarship and a National Institute for Health Research Comprehensive Biomedical Research Centre.