Molecular analysis of tammar (Macropus eugenii) mammary epithelial cells stimulated with lipopolysaccharide and lipoteichoic acid
Kerry A Daly, Sonia L Mailer, Matthew R Digby, Christophe Lefevre, Peter Thomson, Elizabeth Deane, Kevin R Nicholas, Peter Williamson
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY | ELSEVIER | Published : 2009
The immunological function of the metatherian mammary gland plays a crucial part in neonatal survival of the marsupial young. Marsupial pouch young do not develop adult like immune responses until just prior to leaving the pouch. The immune components of the maternal milk secretions are important during this vulnerable early post-partum period. In addition, infection of the mammary gland has not been recognized in metatherians, despite the ready availability of pathogens in the pouch. Regardless of which, little is known about the immunobiology of the mammary gland and the immune responses of mammary epithelial cells in metatherians. In this study, a molecular approach was utilized to examin..View full abstract
This work was supported in part by an Australian Postgraduate Award (KD) from the University of Sydney. The authors also wish to thank Mr Ron Claassens, Ms Anne Mouland-Claassens and MS Rebecca Carman for their assistance in collection of samples.