Journal article

The role of proteomics in defining the human embryonic secretome

MG Katz-Jaffe, S McReynolds, DK Gardner, WB Schoolcraft

MOLECULAR HUMAN REPRODUCTION | OXFORD UNIV PRESS | Published : 2009

Abstract

Non-invasive gamete and embryo assessment is considered an important focus in assisted reproductive technologies (ART). Currently, the selection of embryos for transfer is based on morphological indices. Though successful, the field of ART would benefit from a non-invasive quantitative method of viability determination. Omics technologies, including transcriptomics, proteomics and metabolomics, have already begun providing evidence that viable gametes and embryos possess unique molecular profiles with potential biomarkers that can be utilized for developmental and/or viability selection. Unlike the human genome that is relatively fixed and steady throughout the human body, the human proteome..

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University of Melbourne Researchers