Importance of antibody and complement for oxidative burst and killing of invasive nontyphoidal Salmonella by blood cells in Africans
Esther N Gondwe, Malcolm E Molyneux, Margaret Goodall, Stephen M Graham, Pietro Mastroeni, Mark T Drayson, Calman A MacLennan
Proceedings of the National Academy of Sciences of the United States of America | NATL ACAD SCIENCES | Published : 2010
Awarded by Medical Research Council
We thank the parents, guardians, and children who participated in this study. We are grateful to Mr. Paul Pensulo and nurses Meraby Funsani and Grace Mwimaniwa for their help in recruiting children and Professor Elizabeth Molyneux and Professor Eric Borgstein and the staff at Queen Elizabeth Central Hospital, Beit Cure International Hospital, and the Malawi-Liverpool-Wellcome Trust Clinical Research Programme for their assistance. We thank Dr. Robert Kingsley ( Wellcome Trust Sanger Institute) for providing the galE<SUP>-</SUP> mutant of S. Typhimurium D23580. This work was supported by a PhD studentship from the Training Committee of the Malawi-Liverpool-Wellcome Trust Clinical Research Programme( to E.N.G.), a Tropical Research Fellowship ( to C. A. M.) and a Programme Grant ( to M.E.M.) from the Wellcome Trust, and a Clinical Research Fellowship from GlaxoSmithKline ( to C. A. M.).