Bacteremia in Malawian children with severe malaria: Prevalence, etiology, HIV coinfection, and outcome

Rachel N Bronzan; Terrie E Taylor; James Mwenechanya; Madalitso Tembo; Kondwani Kayira; Lloyd Bwanaisa; Alfred Njobvu; Wendy Kondowe; Chipo Chalira; Amanda L Walsh; Amos Phiri; Lorna K Wilson; Malcolm E Molyneux; Stephen M Graham

Journal article

Bacteremia in Malawian children with severe malaria: Prevalence, etiology, HIV coinfection, and outcome

Rachel N Bronzan, Terrie E Taylor, James Mwenechanya, Madalitso Tembo, Kondwani Kayira, Lloyd Bwanaisa, Alfred Njobvu, Wendy Kondowe, Chipo Chalira, Amanda L Walsh, Amos Phiri, Lorna K Wilson, Malcolm E Molyneux, Stephen M Graham

JOURNAL OF INFECTIOUS DISEASES | UNIV CHICAGO PRESS | Published : 2007

DOI: 10.1086/511437

Abstract

BACKGROUND: Previous prospective studies of bacteremia in African children with severe malaria have mainly included children with cerebral malaria, and no study has examined the impact of human immunodeficiency virus (HIV) infection. We examined the prevalence and etiology of bacteremia and the impact of HIV infection on bacteremia in Malawian children with severe malaria, as well as the impact of bacteremia and HIV infection on outcome. METHODS: From 1996 until 2005, blood for culture was obtained on admission from all children admitted with severe malaria during the rainy season to the Paediatric Research Ward at the Queen Elizabeth Central Hospital in Blantyre, Malawi. HIV testing was per..

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