Do childhood respiratory infections continue to influence adult respiratory morbidity?
SC Dharmage, B Erbas, D Jarvis, M Wjst, C Raherison, D Norback, J Heinrich, J Sunyer, C Svanes
EUROPEAN RESPIRATORY JOURNAL | EUROPEAN RESPIRATORY SOC JOURNALS LTD | Published : 2009
The aim of the present study was to examine the influence of childhood respiratory infections on adult respiratory health. In 1992-1994, the European Community Respiratory Health Survey recruited community based samples of 20-44-yr-old people from 48 centres in 22 countries. Study participants completed questionnaires and underwent lung function testing. On average, 8.9 yrs later, 29 centres re-investigated their samples using similar methods. Mixed effects models comprising an estimate for the random variation between centres were used to evaluate the relevant associations. In total, 9,175 patients participated in both studies, of whom 10.9% reported serious respiratory infections (SRI) bef..View full abstract
Awarded by NATIONAL CENTER FOR RESEARCH RESOURCES
The European Community Respiratory Health Survey (ECRHS) study is a joint project involving many participants and is funded by many sources. The staff involved in the ECRHS study were as follows: P. Burney (project leader); S. Chinn (statistician); D. Jarvis and C. Luczynska (principal investigators); J. Knox (project co-ordinator); J. Potts (assistant statistician); and S. Arinze (data manager; all National Heart and Lung Institute, Imperial College, London, UK).