Journal article
Human papillomavirus genotyping using archival vulval dysplastic or neoplastic biopsy tissues: Comparison between the INNO-LiPA and linear array assays
SE Tan, SM Garland, AR Rumbold, SN Tabrizi
Journal of Clinical Microbiology | AMER SOC MICROBIOLOGY | Published : 2010
DOI: 10.1128/JCM.02311-09
Abstract
The Roche Linear Array (LA) and Innogenetics INNO-LlPA human papillomavirus (HPV) genotyping assays were compared for paraffin-embedded vulval tissues. The LA detected ampllfiable DNA in 28 (57%) out of 49 biopsy specimens, 20 (40%) being HPV genotyped, compared to 49 (100%) and 41 (83%), respectively, detected by the INNO-LiPA. The INNO-LiPA provides greater sensitivity for HPV genotyping in archival tissue. Copyright © 2010, American Society for Microbiology. All Rights Reserved.
Grants
Funding Acknowledgements
S. Tan was supported by The Royal Women's Hospital Postgraduate Degree scholarship from The Royal Women's Hospital, Melbourne, Australia.