Journal article

A Comprehensive Neuropsychiatric Study of Elderly Twins: The Older Australian Twins Study

Perminder S Sachdev, Andrea Lammel, Julian N Trollor, Teresa Lee, Margaret J Wright, David Ames, Wei Wen, Nicholas G Martin, Henry Brodaty, Peter R Schofield

TWIN RESEARCH AND HUMAN GENETICS | CAMBRIDGE UNIV PRESS | Published : 2009

Abstract

The Older Australian Twins Study (OATS) was recently initiated to investigate genetic and environmental factors and their associations and interactions in healthy brain ageing and ageing-related neurocognitive disorders. The study extends the classic MZ-DZ design to include one or two equivalently aged siblings for each twin pair and utilizes the rich resources of the Australian Twin Registry. The study has a number of distinguishing features including comprehensive psychiatric, neuropsychological, cardiovascular, metabolic, and neuroimaging assessments, a longitudinal design and links with a brain donor program. The study measures many behavioral and environmental factors, but in particular..

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University of Melbourne Researchers

Grants

Awarded by NHMRC/ARC


Funding Acknowledgements

We thank the participants of the Older Australian Twins Study and the staff of the Australian Twin Registry. We also thank the SEALS Laboratories of the South Eastern Sydney & Illawarra Area Health Service for blood tests, Symbion Imaging for MRI scans, and Symbion Pathology for blood collection. This study is supported by an NHMRC/ARC Strategic Award Grant of the Ageing Well, Ageing Productively Program (ID No. 401126). Angela Russell assisted with the preparation of the manuscript.