The Central Retinal Vein Bypass Study: A Trial of Laser-induced Chorioretinal Venous Anastomosis for Central Retinal Vein Occlusion
Ian L McAllister, Mark E Gillies, Lynne A Smithies, Elena Rochtchina, Colin A Harper, Mark D Daniell, Ian J Constable, Paul Mitchell
OPHTHALMOLOGY | ELSEVIER SCIENCE INC | Published : 2010
PURPOSE: To evaluate the effectiveness of a laser-induced chorioretinal venous anastomosis (L-CRA) as a treatment for nonischemic central retinal vein occlusion (CRVO). DESIGN: Prospective, randomized, controlled, multicenter clinical trial. PARTICIPANTS: A total of 113 consecutive patients with a nonischemic CRVO of >3 months' duration and visual acuity of < or =20/50. METHODS: Patients were randomized to L-CRA (58 patients) or conventional care (55 patients). They underwent standardized retinal photography, fluorescein angiography, and ophthalmic examinations, together with standardized assessments of best-corrected visual acuity, performed by masked visual acuity assessors using Early Tre..View full abstract
Awarded by Australian National Health and Medical Research Council, Canberra, Australia
Supported by the Australian National Health and Medical Research Council, Canberra, Australia (Grant 990737).