Journal article

Clinical Characteristics and Outcome in Patients With Psychogenic Nonepileptic Seizures

Simon G Jones, Terence J O'Brien, Sophia J Adams, Ramon Mocellin, Christine J Kilpatrick, Raju Yerra, John H Lloyd, Dennis Velakoulis

PSYCHOSOMATIC MEDICINE | LIPPINCOTT WILLIAMS & WILKINS | Published : 2010

Abstract

OBJECTIVES: To examine baseline clinical features of psychogenic nonepileptic seizures (PNES) in a large cohort and to investigate outcome over a period of up to 10 years. Studies investigating PNES have been limited by differences in diagnostic criteria, short follow-up periods, and the use of limited outcome measures. METHOD: Patients with PNES were identified, using strict diagnostic criteria. Baseline neurological, neuropsychiatric, and neuroimaging data were obtained from medical records. Long-term outcome was assessed with ratings of seizures, psychopathology, and quality of life in a subset of the patients. RESULTS: Patients with PNES (n = 221) experienced long delays in diagnosis (mu..

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