Journal article

Emphysema, Airflow Limitation, and Early Age-Related Macular Degeneration

Ronald Klein, Michael D Knudtson, Barbara EK Klein, Tien Y Wong, Mary Frances Cotch, Graham Barr

ARCHIVES OF OPHTHALMOLOGY | AMER MEDICAL ASSOC | Published : 2010

Abstract

OBJECTIVE: To describe the associations of lung function and emphysema, measured with spirometry and computed tomography (CT), with early age-related macular degeneration (AMD) in a sample of white, black, Hispanic, and Chinese subjects. METHODS: Three thousand three hundred ninety-nine persons aged 45 to 84 years residing in 6 US communities participated in a period cross-sectional study. Age-related macular degeneration was measured from digital retinal photographs at the second Multi-Ethnic Study of Atherosclerosis (MESA) examination. Forced expiratory volume in 1 second (FEV(1)) and FEV(1) to forced vital capacity (FVC) ratio were measured at the third or fourth MESA examination. Percent..

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Grants

Awarded by National Heart, Lung and Blood Institute


Awarded by National Eye Institute


Awarded by National Institutes of Health


Awarded by DIVISION OF EPIDEMIOLOGY AND CLINICAL APPLICATIONS


Awarded by NATIONAL EYE INSTITUTE


Awarded by NATIONAL HEART, LUNG, AND BLOOD INSTITUTE


Funding Acknowledgements

This research was supported by contracts N01-HC-95159 through N01-HC-95165 and N01-HC-95169 from the National Heart, Lung and Blood Institute; National Institutes of Health Intramural Research program award Z01000403 from the National Eye Institute (Dr Cotch); and grants HL69979-03 (Drs R. Klein and Wong) and HL077612 (Dr Barr) from the National Institutes of Health.