Primary CTL response magnitude in mice is determined by the extent of naive T cell recruitment and subsequent clonal expansion

Nicole L La Gruta; William T Rothwell; Tania Cukalac; Natasha G Swan; Sophie A Valkenburg; Katherine Kedzierska; Paul G Thomas; Peter C Doherty; Stephen J Turner

Journal article

Primary CTL response magnitude in mice is determined by the extent of naive T cell recruitment and subsequent clonal expansion

Nicole L La Gruta, William T Rothwell, Tania Cukalac, Natasha G Swan, Sophie A Valkenburg, Katherine Kedzierska, Paul G Thomas, Peter C Doherty, Stephen J Turner

Journal of Clinical Investigation | AMER SOC CLINICAL INVESTIGATION INC | Published : 2010

DOI: 10.1172/JCI41538

University of Melbourne Researchers

Stephen Turner Author Microbiology and Immunology

Nicole La Gruta Author Microbiology and Immunology

Peter Doherty Author Microbiology and Immunology

Katherine Kedzierska Author Microbiology and Immunology

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Grants

Awarded by National Health and Medical Research Council (NHMRC)

Awarded by NIH

Awarded by NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES

Funding Acknowledgements

We thank D. Godfrey, F. Carbone, W. Heath, and K. Shortman for reagents and). Rossjohn for critical review of the manuscript. This work was supported by National Health and Medical Research Council (NHMRC) project grants AI454595 (to N.L. La Gruta and P.C. Doherty) and AI454312 (to K. Kedzierska), NHMRC Program grant (AI567122 to P.C. Doherty), NIH grants AI70251 (to P.C. Doherty) and AI065097 (to P.G. Thomas), NHMRC RD Wright Career Development Awards (to N.L. La Gruta and K. Kedzierska), a Pfizer Australia Research Fellowship (to S.J. Turner), an NHMRC Biomedical Postgraduate Scholarship (ID520643 to T. Cukalac), and an Australian-American Fulbright Postgraduate Scholarship (to W.T. Rothwell).