Journal article

Dietary carbohydrate in relation to cortical and nuclear lens opacities in the melbourne visual impairment project

CJ Chiu, L Robman, CA Mccarty, BN Mukesh, A Hodge, HR Taylor, A Taylor

Investigative Ophthalmology and Visual Science | ASSOC RESEARCH VISION OPHTHALMOLOGY INC | Published : 2010

Abstract

PURPOSE. In vitro and in vivo animal studies suggest that dietary carbohydrates play a role in cataractogenesis. Few epidemiologic studies have been conducted to evaluate this association. The objective of this study was to examine the cross-sectional associations between total carbohydrate intake, dietary glycemic index (dGI), and the risk of cortical and nuclear cataracts. METHODS. After excluding 864 persons from 2473 eligible participants, 1609 eligible nondiabetic participants (mean age, 57.6 years, 55.9% female) in the Melbourne Visual Impairment Project (VIP) were enrolled. Dietary information derived from a semiquantitative food-frequency questionnaire and cataract status graded by t..

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University of Melbourne Researchers

Grants

Awarded by National Eye Institute


Funding Acknowledgements

Supported by the U.S. Department of Agriculture under agreements 58-1950-4-401, 1950-5100-060-01A (C-JC, AT); Grants R01-13250 and R03-EY014183-01A2 from the National Institutes of Health (AT); grants (AT) from the Johnson and Johnson Focused Giving Program, the American Health Assistance Foundation, and the Ross Aging Initiative Program (C-JC). Any opinions, findings, conclusions, or recommendations expressed in this publication are those of the authors and do not necessarily reflect the views or policies of the U. S. Department of Agriculture, nor does mention of trade names, commercial products, or organizations imply endorsement by the U. S. Government. The funding sources had no role in the design and conduct of the study; the collection, analysis, and interpretation of the data; or the preparation, review, or approval of the manuscript.