Experience of trauma and conversion to psychosis in an ultra-high-risk (prodromal) group
A Bechdolf, A Thompson, B Nelson, S Cotton, MB Simmons, GP Amminger, S Leicester, SM Francey, C McNab, H Krstev, A Sidis, PD McGorry, AR Yung
ACTA PSYCHIATRICA SCANDINAVICA | WILEY | Published : 2010
OBJECTIVE: We aimed to replicate a recent finding of high prevalence of trauma history in patients at 'ultra-high risk' (UHR) of psychotic disorder and to investigate whether trauma predicts conversion to psychosis in this population. METHOD: A consecutive sample of UHR patients was assessed. History of trauma was accessed with the General Trauma Questionnaire. Cox regression models were used to explore relationship between conversion to psychosis and trauma. RESULTS: Of 92 UHR patients nearly 70% had experienced a traumatic event and 21.7% developed psychosis during follow-up (mean 615 days). Patients who had experienced a sexual trauma (36%) were significantly more likely to convert to fir..View full abstract
Awarded by German Research Foundation
This work was supported by the Colonial Foundation philanthropic trust. AB is supported by a grant from the German Research Foundation (Be 3697/1-1) and an NARSAD Independent Investigator Award. BN is supported by a Ronald Phillip Griffith Fellowship and a NARSAD Young Investigator Award. ARY is supported by a National Health and Medical Research Council (NHMRC) Senior Research Fellowship.