Journal article

Multilayer Buildup and Biofouling Characteristics of PSS-b-PEG Containing Films

Christina Cortez, John F Quinn, Xiaojuan Hao, Chakravarthy S Gudipati, Martina H Stenzel, Thomas P Davis, Frank Caruso

LANGMUIR | AMER CHEMICAL SOC | Published : 2010

Abstract

Thin films exhibiting protein resistance are of interest in diverse areas, ranging from low fouling surfaces in biomedicine to marine applications. Herein, we report the preparation of low protein and cell binding multilayer thin films, formed by the alternate deposition of a block copolymer comprising polystyrene sulfonate and poly(poly(ethylene glycol) methyl ether acrylate) (PSS-b-PEG), and polyallylamine hydrochloride (PAH). Film buildup was followed by quartz crystal microgravimetry (QCM), which showed linear growth and a high degree of hydration of the PSS-b-PEG/PAH films. Protein adsorption studies with bovine serum albumin using QCM demonstrated that multilayer films of PSS/PAH with ..

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