The Lmo2 Oncogene Initiates Leukemia in Mice by Inducing Thymocyte Self-Renewal
Matthew P McCormack, Lauren F Young, Sumitha Vasudevan, Carolyn A de Graaf, Rosalind Codrington, Terence H Rabbitts, Stephen M Jane, David J Curtis
Science | AMER ASSOC ADVANCEMENT SCIENCE | Published : 2010
Awarded by National Health and Medical Research Council of Australia (NHMRC)
Awarded by Medical Research Council UK
Awarded by Leukaemia Research UK
Awarded by Medical Research Council
We thank C. Talora and I. Screpanti for Lck-Notch3-IC transgenic mice; D. Izon for the MIG-Hhex retroviral vector; A. Strasser for comments on the manuscript; G. Smyth for advice on bioinformatics; and L. Ta, R. Bowyer, L. Mizhiritzky, and J. Davis for animal husbandry. This work was supported by grants (to M. P. M., S. M. J., and D. J. C.) from the Cancer Council of Victoria and National Health and Medical Research Council of Australia (NHMRC) (project grant 382901); a grant-in-aid (to M. P. M. and D.J.C.) from the Leukaemia Foundation; and grants (to T. H. R.) from the Medical Research Council UK (programme grant G0600914) and Leukaemia Research UK (programme grant 07036). D.J.C. is an R. D. Wright Biomedical Research Fellow, and S.M.J. is a Principal Research Fellow of the NHMRC.