Journal article

Risk factors associated with acute hip prosthetic joint infections and outcome of treatment with a rifampin-based regimen

Peter FM Choong, Michelle M Dowsey, Derek Carr, John Daffy, Peter Stanley

ACTA ORTHOPAEDICA | TAYLOR & FRANCIS LTD | Published : 2007

Abstract

BACKGROUND AND PURPOSE: Acute prosthetic infection is a serious problem. We report factors related to the incidence of acute infection and results of combined joint debridement and prolonged rifampicin-based antibiotic therapy. PATIENTS AND METHODS: Between 1998 and 2004, 14 acute infections occurred after 819 primary hip arthroplasties. The association between patient-related and surgical factors and the risk of infection were analyzed. Infections were treated with multiple joint lavage, debridement, 2 weeks of antibiotic therapy, and then oral antibiotics for a minimum of 6 months. RESULTS: There was a correlation between having a body mass index (BMI) of >or=30, and also more than 2 co-mo..

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