The Transcription Factor PU.1 Controls Dendritic Cell Development and Flt3 Cytokine Receptor Expression in a Dose-Dependent Manner

Grants

Funding Acknowledgements

We thank A. Kallies, K. Shortman, and G. Belz for comments on the manuscript; K. Elder and N. Bernard for technical assistance; and M. Busslinger (IMP, Vienna Austria) for providing the Flt3<SUP>+/-</SUP> mice and plasmid vectors. This work was supported by the National Health and Medical Research Council (NHMRC) of Australia. S.C. was supported by an Australian Research Council Discovery Fellowship, S.H.M.P. by the Leukaemia Foundation, K.T.G. by a Stella Mary Langford Scholarship from the University of Melbourne, S.L.N. by the Pfizer Australia Research Fellowship, and L.W. by an NHMRC Fellowship. S.C, A. Dakic, and A. D'Amico designed and performed most of the experiments and provided input in the manuscript. S.H.M.P and K.T.G performed analysis of the Flt3 promoter. S.L.N and L.W supervised the experimental design, analyzed experiments, and cowrote the manuscript.