Behavioural phenotype of APPC100.V717F transgenic mice over-expressing a mutant A beta-bearing fragment is associated with reduced NMDA receptor density

Wah Chin Boon; Maarten van den Buuse; Nico Wegener; Sally Martin; Hui Kheng Chua; Ashley I Bush; Colin L Masters; Paul A Adlard; Qiao-Xin Li

Journal article

Behavioural phenotype of APPC100.V717F transgenic mice over-expressing a mutant A beta-bearing fragment is associated with reduced NMDA receptor density

Wah Chin Boon, Maarten van den Buuse, Nico Wegener, Sally Martin, Hui Kheng Chua, Ashley I Bush, Colin L Masters, Paul A Adlard, Qiao-Xin Li

Behavioural Brain Research | ELSEVIER SCIENCE BV | Published : 2010

DOI: 10.1016/j.bbr.2010.01.013

University of Melbourne Researchers

Qiao-Xin Li Author Melbourne Medical School

Ashley Bush Author Florey Department of Neuroscience and Mental Health

Maarten Van Den Buuse Author Biochemistry and Pharmacology

Related Projects (2)

NEURODEGENERATION IN THE AGING BRAIN: HOW THE PATHWAYS LEADING TO AGGREGATED PROTEIN CAUSE DISEASE

The team consists of eight highly experienced research scientists who are dedicated to solving the question of how the brain degenerates in ..

INFLUENCES OF OESTROGEN ON NEURODEGNERATION AND BEHAVIOURS

More women develop Alzheimer's disease whereas more men develop Parkinson's disease. This study will try to understand whether sex hormones ..

Grants

Awarded by NHMRC

Funding Acknowledgements

This work was supported in part by NHMRC program grant #400202 and NHMRC project grant 494813 (W.C. Boon and H.K. Chua). At the time of the experiments, M. van den Buuse was supported by a Griffith Senior Research Fellowship from the University of Melbourne, Australia.