Journal article

Fluid administration and the kidney

John R Prowle, Rinaldo Bellomo

CURRENT OPINION IN CRITICAL CARE | LIPPINCOTT WILLIAMS & WILKINS | Published : 2010

Abstract

PURPOSE OF REVIEW: Intravenous fluids are widely administered in the ICU with the intention of preventing or ameliorating acute kidney injury (AKI). This review focuses on recent studies examining fluid administration and renal function in critical illness to critically examine conventional justifications for fluid administration. RECENT FINDINGS: Early, targeted, resuscitation of inadequate cardiac output in shock may have a beneficial effect on organ function and patient outcome. However, experimental evidence suggests the relationship between fluid administration and an increase in renal oxygen delivery is weak, whereas any beneficial effects from fluid administration can be short lived. ..

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University of Melbourne Researchers