Brain imaging in transient ischemic attack - redefining TIA
Aleksandra M Pavlovic, Christen D Barras, Peter J Hand, Brian M Tress, Patricia M Desmond, Stephen M Davis
JOURNAL OF CLINICAL NEUROSCIENCE | ELSEVIER SCI LTD | Published : 2010
Transient ischemic attack (TIA) has recently been redefined to incorporate the latest clinical and neuroimaging information that has shed new light on TIA pathophysiology. Patients suffering from TIA are at a substantial risk of subsequent stroke, but quantifying this risk is difficult as TIA patients are a heterogeneous population and there are multiple TIA mimics. Clinical scores for prediction of stroke risk are principally based on patient history and potentially understate actual risk. Magnetic resonance imaging (MRI), in particular diffusion-weighted imaging (DWI) performed in the first days following TIA, reveals relevant focal ischemic abnormalities in 21-68% of patients. These lesio..View full abstract
Dr. Barras receives funding from the National Health and Medical Research Council (NHMRC), a CVL Pfizer Research Grant, and the Royal Melbourne Hospital Neuroscience Foundation.