Differential contributions of objective memory and mood to subjective memory complaints in refractory focal epilepsy

Abstract

People with epilepsy frequently present with bitter memory complaints. Previous research variously attributes this to symptoms of mood disturbance or objective memory deficits. To investigate the influence of the epileptogenic region on this variability, we examined interrelationships between mood, objective memory, and memory complaints in a sample of patients with refractory focal epilepsy and controls (N= 96). Patients had either mesial temporal (MT, n= 39) or non mesial-temporal (NMT, n= 21) foci. In contrast to controls (n= 36), both patient groups were highly concerned about their memory (P<. 0.001) and were more likely to have a history of depression (P= 0.005). Multiple regression sh..