Journal article
Recent developments in prostate cancer biomarker research: Therapeutic implications
S Detchokul, AG Frauman
British Journal of Clinical Pharmacology | WILEY | Published : 2011
Abstract
This review aims to present an overview of recent clinical trials targeting biomarkers in advanced prostate cancer. We searched ClinicalTrials.gov for early phase clinical trials on treatments of prostate cancer that have been recently completed, are ongoing or are actively recruiting participants. Drug targets and their mechanism of actions were assessed and summarized. Trials were categorized according to prostate cancer biomarkers that have potential as therapeutic targets. A total of 19 new therapeutic agents for the treatment of prostate cancer are included in this review. Trials are summarized according to the targeted biomarkers and are categorized into five therapeutic approaches: pr..
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Funding Acknowledgements
Sujitra Detchokul was a recipient of a Medical & Scientific Kidney & Urology related Research Biomedical Research Scholarship from Kidney Health Australia and a University of Melbourne Fee Remission Scholarship from The University of Melbourne. This work was supported by the Austin Hospital Medical Research Foundation and the Sir Edward Dunlop Medical Research Foundation.