Journal article

Development of optimized vascular fractal tree models using level set distance function

Anh V Bui, Richard Manasseh, Kurt Liffman, Ilija D Sutalo

MEDICAL ENGINEERING & PHYSICS | ELSEVIER SCI LTD | Published : 2010

Abstract

Using the concepts of fractal scaling and constrained constructive optimization (CCO), a branching tree model, which has physiologically meaningful geometric properties, can be constructed. A vascular branching tree model created in this way, although statistically correct in representing the vascular physiology, still does not possess a physiological correct arrangement of the major arteries. A distance-function based technique for "staged growth" of vascular models has been developed in this work to address this issue. Time-dependent constraints based on a signed-distance level set function have been added, so that the tree models will first be grown near the designated surface(s) and, the..

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University of Melbourne Researchers