In vivo anthelmintic activity of Azadirachta indica A. Juss seeds against gastrointestinal nematodes of sheep

Abstract

This paper describes the in vivo anthelmintic activity of Azadirachta indica seeds to justify their use in South-Asia by traditional animal healers. Seeds of A. indica were administered as crude powder (CP), crude aqueous (CAE) and crude methanolic extracts (CME) at the doses of 1 and 3 g/kg of body weight to sheep naturally infected with mixed species of gastrointestinal nematodes. The study design also included untreated as well as treated controls. Faecal egg count reduction and larval counts from coprocultures were performed pre- and post-treatments to assess the anthelmintic activity. Crude powder and CME did not show significant activity (P > 0.05) at the lower dose used but were found..