Fact or hypothesis: Taenia crassiceps as a model for Taenia solium, and the S3Pvac vaccine
Parasite Immunology | WILEY | Published : 2010
Research undertaken over the past 40 years has established many of the general principals concerning immunity to taeniid cestodes. Although much is well understood about the host-protective mechanisms against taeniids and this knowledge has been exploited in studies on vaccine development, many aspects require further investigation or confirmation. Some phenomena have come to be regarded as being well established, while careful analysis of the published data would suggest that they may be better regarded as hypotheses rather than established facts. This review considers one selected issue pertaining to immunity to cestode infections and examines carefully the nature of the evidence that is a..View full abstract
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Awarded by Wellcome Trust
Awarded by Australian National Health and Medical Research Council
Funding from The Wellcome Trust, Animal Health in the Developing World Grant 075818 and the Australian National Health and Medical Research Council grants 350279, 400109 and 628320 are acknowledged. Charles Gauci and Garry Anderson provided valuable comments and assistance during preparation of the manuscript.