Troponin I and NT-proBNP (N-terminal pro-Brain Natriuretic Peptide) do not predict 6-month mortality in frail older patients undergoing orthopedic surgery

CP Chong; WJ van Gaal; JE Ryan; LM Burrell; J Savige; WK Lim

Journal article

Troponin I and NT-proBNP (N-terminal pro-Brain Natriuretic Peptide) do not predict 6-month mortality in frail older patients undergoing orthopedic surgery

CP Chong, WJ van Gaal, JE Ryan, LM Burrell, J Savige, WK Lim

Journal of the American Medical Directors Association | Published : 2010

DOI: 10.1016/j.jamda.2010.01.003

Abstract

Objectives: To determine if troponin I and NT-proBNP were predictors of 6-month mortality after emergency orthopedic-geriatric surgery in a frail population. Design: Prospective observational study. Setting: Orthopedic-geriatric unit of a metropolitan hospital in Australia. Participants: A total of 383 patients were screened; 44 were eligible for this study of which 33 patients consented who were receiving high-level care or had severe dementia or an illness with a prognosis of less than 12 months. Measurements: Troponin I and NT-proBNP were tested on one preoperative sample and at least one postoperative blood sample. Cardiac events were defined as acute myocardial infarction, congestive ca..

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University of Melbourne Researchers

Bill van Gaal Author

Louise Burrell Author

Judith Savige Author

Wen Kwang Lim Author

Grants

Funding Acknowledgements

This study was sponsored by a Cardiovascular Lipid grant from Pfizer. Dr Carol Chong is a recipient of an National Health and Medical Research Council (Australia) postgraduate research scholarship and has received research stipends from The University of Melbourne and the Northern Clinical Research Centre, Northern Health.