Journal article
The effect of acute exercise on undercarboxylated osteocalcin in obese men
I Levinger, R Zebaze, G Jerums, DL Hare, S Selig, E Seeman
Osteoporosis International | Published : 2011
Abstract
The purpose of this study was to examine if the reduction in glucose post-exercise is mediated by undercarboxylated osteocalcin (unOC). Obese men were randomly assigned to do aerobic or power exercises. The change in unOC levels was correlated with the change in glucose levels post-exercise. The reduction in glucose post-acute exercise may be partly related to increased unOC. Introduction: Osteocalcin (OC) in its undercarboxylated (unOC) form may contribute to the regulation of glucose homeostasis. As exercise reduces serum glucose and improves insulin sensitivity in obese individuals and individuals with type 2 diabetes (T2DM), we hypothesised that this benefit was partly mediated by unOC. ..
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Funding Acknowledgements
The authors wish to thank Dr. Thuy Vu for her assistance in recruitment and screening of volunteers. This study was partly funded by the Helen Macpherson Smith Trust and Victoria University Development Grant.