Epigenetic silencing of BIM in glucocorticoid poor-responsive pediatric acute lymphoblastic leukemia, and its reversal by histone deacetylase inhibition
Petra S Bachmann, Rocco G Piazza, Mary E Janes, Nicholas C Wong, Carwyn Davies, Angela Mogavero, Vivek A Bhadri, Barbara Szymanska, Greta Geninson, Vera Magistroni, Giovanni Cazzaniga, Andrea Biondi, Diego Miranda-Saavedra, Berthold Goettgens, Richard Saffery, Jeffrey M Craig, Glenn M Marshall, Carlo Gambacorti-Passerini, John E Pimanda, Richard B Lock
Blood | AMER SOC HEMATOLOGY | Published : 2010
Awarded by Associazione Italiana Ricerca sul Cancro (AIRC)
Awarded by Medical Research Council
Awarded by National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs)
This work was supported by the Children's Cancer Institute Australia for Medical Research, a fellowship (R.B.L.) and grants from The Australian National Health and Medical Research Council and the Anthony Rothe Memorial Trust, a University Postgraduate Award from the University of New South Wales (P.S.B.), an Australian Postgraduate Award (C.D.), the Center for Children's Cancer and Blood Disorders, Sydney Children's Hospital (V.A.B.), by a Postgraduate Scholarship from the Leukemia Foundation of Australia (V.A.B.), by the Associazione Italiana Ricerca sul Cancro (AIRC, IG-4637). and by the Italian Prin program-Ministry of University and Research (PRIN-MIUR).