Journal article

Prevalence of mood and anxiety disorder in self reported irritable bowel syndrome (IBS). An epidemiological population based study of women

Arnstein Mykletun, Felice Jacka, Lana Williams, Julie Pasco, Margaret Henry, Geoffrey C Nicholson, Mark A Kotowicz, Michael Berk



BACKGROUND: Irritable bowel syndrome (IBS) is commonly regarded as a functional disorder, and is hypothesized to be associated with anxiety and depression. This evidence mainly rests on population-based studies utilising self-report screening instruments for psychopathology. Other studies applying structured clinical interviews are generally based on small clinical samples, which are vulnerable to biases. The extant evidence base for an association between IBS and psychopathology is hence not conclusive. The aim of this study was therefore to re-examine the hypothesis using population-based data and psychiatric morbidity established with a structured clinical interview. METHODS: Data were de..

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Awarded by National Health and Medical Research Council of Australia

Funding Acknowledgements

The data collection was funded by the National Health and Medical Research Council of Australia (251638) and supported by an unrestricted educational grant from Eli Lilly. The University of Melbourne, Faculty of Medicine, Dentistry and Health Sciences and the Australian Rotary Health Research Fund provided postgraduate scholarships to LW and FJ. The first author was funded as post doctor by the Research Council of Norway.