Journal article
New directions in childhood obesity research: How a comprehensive biorepository will allow better prediction of outcomes
MA Sabin, SL Clemens, R Saffery, Z McCallum, MW Campbell, W Kiess, NA Crimmins, JG Woo, GM Leong, GA Werther, OC Ukoumunne, MA Wake
BMC Medical Research Methodology | BMC | Published : 2010
Abstract
Background. Childhood obesity is associated with the early development of diseases such as type 2 diabetes and cardiovascular disease. Unfortunately, to date, traditional methods of research have failed to identify effective prevention and treatment strategies, and large numbers of children and adolescents continue to be at high risk of developing weight-related disease. Aim. To establish a unique 'biorepository' of data and biological samples from overweight and obese children, in order to investigate the complex 'gene × environment' interactions that govern disease risk. Methods. The 'Childhood Overweight BioRepository of Australia' collects baseline environmental, clinical and anthropomet..
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Awarded by Murdoch Children's Research Institute
Funding Acknowledgements
This manuscript, and the work contained within it, is presented on behalf of members of the Murdoch Childrens Research Institute M_POWR (Multidisciplinary Paediatric Obesity & Weight Research) group and is also endorsed by the council of the German competence network of obesity (Kompetenznetz Adipositas) of the German Ministry of Research and Education. WK is a vice chair of the German competence network of obesity and is supported by Deutsche Forschungsgemeinschaft (DFG, German Research Council), Bonn, Germany, and German Ministry of Research and Education (BMBF). OU is funded by an Australian National Health and Medical Research Council Population Health Capacity Building Grant (436914). The study has received significant internal 'start-up' funding from the Murdoch Childrens Research Institute for which all investigators are extremely grateful. We are also indebted to Ms D Hartsorn and Ms K Gibbons who have been actively involved in COBRA recruitment through the Royal Children's Hospital Weight Management Service in Melbourne.