Journal article

Altered microglial copper homeostasis in a mouse model of Alzheimer's disease

Zhiqiang Zheng, Carine White, Jaekwon Lee, Troy S Peterson, Ashley I Bush, Grace Y Sun, Gary A Weisman, Michael J Petris

Journal of Neurochemistry | WILEY | Published : 2010

DOI: 10.1111/j.1471-4159.2010.06888.x

Grants

Awarded by NIH

Funding Acknowledgements

We thank Michelle Mooney for excellent technical support and Drs. Eipper and Donato for reagents. This work was supported by NIH grants DK59893 and AG018357.

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Keywords

Homeostasis
Copper-Transporting Atpases
Nmda Receptor
Brain
Atp7a
Ifn-Gamma
Mice
Science & Technology
Animals
Neurosciences
Protein Transgenic Mice
Plaque, Amyloid
Hydrogen-Peroxide
Targeting A-Beta
Histochemically-Reactive Zinc
Microglia
Cytoplasmic Vesicles
Copper Transporter 1
P-Type Atpase
Cell Line
Neurosciences & Neurology
Protein Transport
Adenosine Triphosphatases
Regulated Trafficking
Inflammation
Copper
Mice, Transgenic
Copper Homeostasis
Alzheimer Disease
Beta-Amyloid Deposition
Biochemistry & Molecular Biology
Alzheimer'S Disease
Interferon-Gamma
Cation Transport Proteins
Life Sciences & Biomedicine