Prevalence of fractionated electrograms in the coronary sinus: Comparison between patients with persistent or paroxysmal atrial fibrillation and a control population

Abstract

Background: Complex fractionated atrial electrograms (CFAEs) are often identified as targets for radiofrequency ablation in the coronary sinus (CS) of patients with atrial fibrillation (AF). Objective: The purpose of this study was to determine whether similar features are present in a normal control population. Methods: Twenty-four patients with AF (12 paroxysmal, 12 persistent) were compared with 12 controls (undergoing radiofrequency ablation for supraventricular tachycardia) in whom at least 1 minute of AF was induced by rapid atrial pacing. Electrogram comparisons during sinus rhythm and AF were made offline. A random 10-second window of AF was used for analysis of fractionation and dom..