Journal article

Lens opacity and refractive influences on the measurement of retinal vascular fractal dimension

Haitao Li, Paul Mitchell, Gerald Liew, Elena Rochtchina, Annette Kifley, Tien Y Wong, Wynne Hsu, Mong L Lee, Yong P Zhang, Jie J Wang

ACTA OPHTHALMOLOGICA | WILEY-BLACKWELL | Published : 2010

Abstract

PURPOSE: To examine the influence of lens opacity and refraction on the measurement of retinal vascular fractal dimension (Df). METHODS:   Optic disc photographs (right eyes) of 3654 baseline Blue Mountains Eye Study participants (aged 49-97) were digitized. Retinal vascular Df was quantified using a computer-based program. Summated severity scores for nuclear, cortical and posterior subcapsular (PSC) cataract were assessed from lens photographs. Refraction data were converted to spherical equivalent refraction (SER), as sum spherical plus 0.5 cylinder power. Axial length was measured at 10-year follow-up examinations using an IOL master. RESULTS:   Mean Df of the retinal vasculature was 1.4..

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Grants

Awarded by Australian National Health & Medical Research Council (NHMRC)


Awarded by Singapore Bioimaging Consortium (SBIC)


Awarded by Biomedical Research Council


Funding Acknowledgements

PM and JJW are funded by Australian National Health & Medical Research Council (NHMRC, Project grant IDs: 153948, 211069 & 30 2068). TYW and PM are funded by Singapore Bioimaging Consortium (SBIC RP C-011/2006) and Biomedical Research Council (Grant No 501/1/25-5). GL, JJW, TYW and PM are funded by Pfizer Australia (Cardiovascular Lipid Grant 2007) and Diabetes Australia Research Trust (DART Grant 2007). JJW is funded by a NHMRC Senior Research Fellowship (2005-2014).