Protein disulphide isomerase protects against protein aggregation and is S-nitrosylated in amyotrophic lateral sclerosis

Grants

Funding Acknowledgements

We thank Professor Neil Bulleid, University of Manchester, for the pCMV5 vector encoding human PDI, and Professor Neil Cashman, University of Toronto, for the NSC-34 cell line. We also thank Dr Bradley Turner for helpful input on the manuscript, and Kai Ying Soo and Professor Philip Nagley for technical assistance and access to unpublished data. Human spinal cord tissues were received from the MND Research Tissue Bank of Victoria, supported by the Victorian Brain Bank Network, the Mental Health Research Institute, Alfred Hospital, Victorian Forensic Institute of Medicine, The University of Melbourne, and funded by MND Research Institute of Australia and the Bethlehem Griffiths Research Foundation.