Journal article

Greater superior than inferior parietal lobule activation with increasing rotation angle during mental rotation: An fMRI study

Andrea Gogos, Maria Gavrilescu, Sonia Davison, Karissa Searle, Jenny Adams, Susan L Rossell, Robin Bell, Susan R Davis, Gary F Egan

Neuropsychologia | PERGAMON-ELSEVIER SCIENCE LTD | Published : 2010

Abstract

Mental rotation is a task known to activate the parietal cortical regions. The present study aimed to investigate whether there is differential activation of regions within the parietal lobe and to reveal functional subspecialisation of this region by examining the effects of increasing angle of rotation. Functional magnetic resonance imaging was performed in nine healthy female subjects whilst undertaking a parametric mental rotation task. The task comprised 6 alphanumeric characters presented in their normal or mirror-reversed orientation. Behaviourally, subjects showed increased reaction times with increased angle of rotation, with differential effects between the alphanumeric characters;..

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Grants

Awarded by Australian National Health and Medical Research Council (NHMRC)


Awarded by Peter Doherty Fellowship


Awarded by Research Training Fellowship


Funding Acknowledgements

This work was supported by the Australian National Health and Medical Research Council (NHMRC) Principal Research Fellowship (Grant 400317, G.F. Egan and Grant 490938, S.R. Davis), Peter Doherty Fellowship (Grant 435690, A. Gogos) and Research Training Fellowship (Grant 465145, S. Davison); the Neurosciences Victoria Neuro-informatics Platform; Vincent Fairfax Family Foundation Fellowship; Royal Australasian College of Physicians, Research and Education Foundation (S. Davison); and FemPharm Pty. Ltd. (a wholly owned subsidiary of Acrux Limited). We thank all the participants in our study, Dr. Michael Ditchfield and Michael Keane at the Murdoch Children's Research Institute MRI facility for invaluable assistance during data acquisition. We also thank David O'Connor and Nicole Joshua for their assistance with task development.