Natural History of Branch Retinal Vein Occlusion: An Evidence-Based Systematic Review

Abstract

Objective: To describe the natural history of branch retinal vein occlusion (BRVO) based on the best available evidence from the literature. Clinical Relevance: Branch retinal vein occlusion is the second most frequent major retinal vascular disease. Although several new treatments for BRVO are currently being introduced, data on its natural history are sparse. Methods: English language articles were retrieved using a keyword search of MEDLINE, EMBASE, Current Contents, and the Cochrane Library to November 13, 2008, supplemented by manually searching the references of review articles published within the last 5 years. All relevant observational studies evaluating the natural history of BRVO ..