Journal article
Abdominal obesity and other risk factors largely explain the high CRP in Indigenous Australians relative to the general population, but not gender differences: A cross-sectional study
AM Hodge, L Maple-Brown, J Cunningham, J Boyle, T Dunbar, T Weeramanthri, J Shaw, K O'Dea
BMC Public Health | BMC | Published : 2010
Abstract
Background. Previous studies reported high C-reactive protein (CRP) levels in Indigenous Australians, which may contribute to their high risk of cardiovascular disease. We compared CRP levels in Indigenous Australians and the general population, accounting for obesity and other risk factors. Methods. Cross-sectional study of CRP and risk factors (weight, height, waist and hip circumferences, blood pressure, lipids, blood glucose, and smoking status) in population-based samples from the Diabetes and Related conditions in Urban Indigenous people in the Darwin region (DRUID) study, and the Australian Diabetes, Obesity and Lifestyle study (AusDiab) follow-up. Results. CRP concentrations were hig..
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Awarded by National Health and Medical Research Council
Funding Acknowledgements
The DRUID Study was funded by the National Health and Medical Research Council (Project Grant #236207), with additional support from the Australian Government Department of Employment and Workplace Relations, the Clive and Vera Ramaciotti Foundation, the Vincent Fairfax Family Foundation, the AusDiab Partnership in Type 2 Diabetes, and Bayer HealthCare. The DRUID Study is an in-kind project of the cooperative Research Centre for Aboriginal Health. LMB had a NHMRC Scholarship 20035 and is supported by the Centre of Clinical Research Excellence in Clinical Science in Diabetes, University of Melbourne. AH is supported by NHMRC Fellowship (520316) and JC was supported by an NHMRC Career Development Award (No. 283310) and NHMRC Research Fellowship (No. 545200).The AusDiab study co-ordinated by the Baker IDI Heart and Diabetes Institute gratefully acknowledges the generous support given by the National Health and Medical Research Council (NHMRC grant 233200), Australian Government Department of Health and Ageing, Amgen, Abbott Australasia Pty Ltd, Alphapharm Pty Ltd, AstraZeneca, Bristol-Myers Squibb, City Health Centre-Diabetes Service-Canberra, Department of Health and Community Services-Northern Territory, Department of Health and Human Services-Tasmania, Department of Health-New South Wales, Department of Health-Western Australia, Department of Health-South Australia, Department of Human Services-Victoria, Diabetes Australia, Diabetes Australia Northern Territory, Eli Lilly Australia, Estate of the Late Edward Wilson, Glaxo-SmithKline, Jack Brockhoff Foundation, Janssen-Cilag, Kidney Health Australia, Marian & FH Flack Trust, Menzies Research Institute, Merck Sharp & Dohme, Novartis Pharmaceuticals, Novo Nordisk Pharmaceuticals, Pfizer Pty Ltd, Pratt Foundation, Queensland Health, Roche Diagnostics Australia, Royal Prince Alfred Hospital, Sydney, Sanofi Aventis, Sanofi Synthelabo.