Regional distribution of blood volume within the preterm infant thorax during synchronised mechanical ventilation

HR Carlisle; RK Armstrong; PG Davis; A Schibler; I Frerichs; DG Tingay

Journal article

Regional distribution of blood volume within the preterm infant thorax during synchronised mechanical ventilation

HR Carlisle, RK Armstrong, PG Davis, A Schibler, I Frerichs, DG Tingay

Intensive Care Medicine | Published : 2010

DOI: 10.1007/s00134-010-2049-4

Abstract

Purpose: Perfusion in healthy adults is gravity-dependent. Little is known about lung perfusion in the preterm infant. The aim of this study was to describe the regional distribution of blood volume within the thorax in preterm infants receiving synchronised volume-targeted mechanical ventilation (SIPPV + TTV) and to compare this to regional distribution of tidal ventilation using electrical impedance tomography (EIT). Methods: Stable supine ventilated preterm infants (<32-week gestation) were studied. Three sets of artefact-free 30-s EIT recordings of the right hemithorax were filtered in the cardiac and respiratory frequency domains to differentiate impedance change due to blood (ΔZc) and ..

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University of Melbourne Researchers

Peter Davis Author

David Tingay Author

Grants

Awarded by National Health and Medical Research Council

Funding Acknowledgements

The authors wish to thank Brenda Argus and Stephanie Tan-Kristanto for their assistance with this study. D. G. T. is supported by a National Health and Medical Research Council Clinical Research Fellowship (Grant ID 491286), P. G. D. is supported by a NHMRC Practitioner Fellowship.