Journal article

Two haplotypes of the P2X(7) receptor containing the Ala-348 to Thr polymorphism exhibit a gain-of-function effect and enhanced interleukin-1 beta secretion

Leanne Stokes, Stephen J Fuller, Ronald Sluyter, Kristen K Skarratt, Ben J Gu, James S Wiley

FASEB Journal | FEDERATION AMER SOC EXP BIOL | Published : 2010

Grants

Funding Acknowledgements

L.S. conducted the majority of experiments and analyzed data; L.S., B.J.G., and J.S.W. designed experiments; S.J.F. conducted haplotype analysis; K.K.S. performed genotyping; R.S. contributed data for Fig. 6; L.S. and J.S.W. wrote the manuscript; and S.J.F., K.K.S, R.S., and B.J.G. contributed to the writing of the manuscript. The authors are grateful to Leah McKinnon for collection of blood for experiments on native cells. This work is funded by the National Health and Medical Research Council of Australia, Leukemia Research Foundation (Australia), and Cure Cancer Australia. The authors acknowledge equipment grants awarded by the University of Sydney Faculty of Medicine and Nepean Medical Research Foundation to L.S. and J.S.W. for the purchase of electrophysiology equipment.