Creating transplant tolerance by taming adverse intragraft innate immunity.
Dusan Hanidziar, Maria Koulmanda, Terry B Strom
F1000 Biol Rep | Faculty Opinions Ltd | Published : 2010
Certain forms of inflammation of an allograft are highly detrimental to the induction and maintenance of transplant tolerance as they foster stable commitment to graft-destructive, not graft-protective, forms of T-cell immunity. Hence, a reduction in adverse tissue inflammation may prove crucial in facilitating the induction and maintenance of a long-lasting state of transplant tolerance.
Awarded by NIAID NIH HHS
Awarded by NIDDK NIH HHS