The chemically synthesized human relaxin-2 analog, B-R13/17K H2, is an RXFP1 antagonist
Mohammed Akhter Hossain, Chrishan S Samuel, Claudia Binder, Tim D Hewitson, Geoffrey W Tregear, John D Wade, Ross AD Bathgate
Amino Acids | SPRINGER | Published : 2010
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Awarded by National Health and Medical Research Council (NHMRC) of Australia
This study was funded by a grant to JDW, GWT, and RADB from the National Health and Medical Research Council (NHMRC) of Australia (ID no. 508995). RADB, JDW, and GWT are recipients of Research Fellowship from the NHMRC, while CSS is the recipient of a National Heart Foundation of Australia/NHMRC RD Wright Fellowship. We would like to thank Sharon Layfield and Tania Ferraro for performing the binding and the cAMP assays, Matthias Schulz for technical assistance with the MCF-7 invasion assays, and Ishanee Mookerjee for assistance with the renal myofibroblast differentiation assays.