Clinical and experimental links between diabetes and glaucoma
Vickie HY Wong, Bang V Bui, Algis J Vingrys
CLINICAL AND EXPERIMENTAL OPTOMETRY | TAYLOR & FRANCIS LTD | Published : 2011
Glaucoma is a leading cause of blindness. It is a multifactorial condition, the risk factors for which are increasingly well defined from large-scale epidemiological studies. One risk factor that remains controversial is the presence of diabetes. It has been proposed that diabetic eyes are at greater risk of injury from external stressors, such as elevated intraocular pressure. Alternatively, diabetes may cause ganglion cell loss, which becomes additive to a glaucomatous ganglion cell injury. Several clinical trials have considered whether a link exists between diabetes and glaucoma. In this review, we outline these studies and consider the causes for their lack of concordant findings. We al..View full abstract
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Awarded by NHMRC
The authors are supported by NHMRC project grants 400127, 475603, 566570 and 350224.