Journal article

Levosimendan preserves the contractile responsiveness of hypoxic human myocardium via mitochondrial K-ATP channel and potential pERK 1/2 activation

Paul F Soeding, Peter J Crack, Christine E Wright, James A Angus, Colin F Royse

European Journal of Pharmacology | ELSEVIER SCIENCE BV | Published : 2011

DOI: 10.1016/j.ejphar.2010.12.035

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Keywords

Myocardium
Heart Atria
Science & Technology
Cardiac Myocytes
Mitogen-Activated Protein Kinase 3
Pharmacology & Pharmacy
Human Right Atrium Levosimendan
Heart
Cell Hypoxia
Muscle Contraction
Ischemic Preconditioning, Myocardial
Enzyme Activation
in Vitro Techniques
Reperfusion Injury
Mitogen-Activated Protein Kinase 1
Simendan
Phosphoproteins
Isoproterenol
Life Sciences & Biomedicine
Apoptosis
Proto-Oncogene Proteins C-Akt
Adrenergic Beta-Agonists
Differential Activation
P38 Mitogen-Activated Protein Kinases
Hydrazones
Caspase 3
Humans
Simulated Ischemia
Potassium Channels
Sensitive Potassium Channels
Protein-Kinase
Oxidative Stress
Pyridazines
Mitochondria
Infarct Size
Cytochromes C
Oxygen
Hypoxia-Reoxygenation
Prosurvival Mediator