Design, Synthesis, and Characterization of a Single-Chain Peptide Antagonist for the Relaxin-3 Receptor RXFP3
Linda M Haugaard-Kedstrom, Fazel Shabanpoor, Mohammed Akhter Hossain, Richard J Clark, Philip J Ryan, David J Craik, Andrew L Gundlach, John D Wade, Ross AD Bathgate, K Johan Rosengren
Journal of the American Chemical Society | AMER CHEMICAL SOC | Published : 2011
This work was supported by grants from the foundations Bengt Lundquist Minne and Helge Ax:son-Jonson Stiftelse to L.M.H.-K and the Faculty of Natural Science and Engineering, Linnaeus University, to K.J.R. Work in the laboratories of A.L.G., D.J.C., J.D.W., and RA.D.B. was supported by the National Medical and Health Research Council (NHMRC) of Australia. K.J.R and R.J.C. are NHMRC Biomedical CDA Fellows. A.L.G. and R.A.D.B. are NHMRC Senior Research Fellows. D.J.C and J.D.W. are NHMRC Principal Research Fellows. R.J.C. gratefully acknowledges the Australian Academy of Science for travel funding. We thank Sharon Layfield for providing transfected cells for the binding and signaling assays.