Journal article

Prevention of cervical cancer in rural China: Evaluation of HPV vaccination and primary HPV screening strategies

K Canfell, JF Shi, JB Lew, R Walker, FH Zhao, L Simonella, JF Chen, R Legood, MA Smith, C Nickson, YL Qiao

Vaccine | Published : 2011

Abstract

Comprehensive evaluation of the cost-effectiveness of HPV vaccination in China has not previously been performed. The objective of this study was to evaluate vaccination as an alternative or addition to primary HPV screening with careHPV (Qiagen, Gaithersburg, USA), and to assess the threshold total cost per vaccinated girl (CVG) at which strategies involving vaccination would become viable compared to screening-only strategies in rural China. We used data from field studies in Shanxi Province to support modelling of HPV vaccination and screening, including local information on sexual behaviour, HPV prevalence, test accuracy, treatment protocols and costs. We evaluated several strategies inv..

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University of Melbourne Researchers

Grants

Funding Acknowledgements

This work was supported by Cancer Council NSW, Australia, and the Chinese Ministry of Science and Technology's Program "National key Technology R&D Program in the 11th Five-Year Plan" [2006BAI02A15]. Dr. Shi was supported by a UICC American Cancer Society Beginning Investigators Fellowship funded by the American Cancer Society [ACS/09/008] and by the Cancer Council NSW. The funding source(s) had no role in the design and conduct of the study; collection, management, analysis and interpretation of the data; or preparation, review, or approval of the manuscript.