Validation of two Framingham cardiovascular risk prediction algorithms in an Australian population: the 'old' versus the 'new' Framingham equation
Ella Zomer, Alice Owen, Dianna J Magliano, Danny Liew, Chris Reid
EUROPEAN JOURNAL OF CARDIOVASCULAR PREVENTION & REHABILITATION | SAGE PUBLICATIONS LTD | Published : 2011
BACKGROUND: Multivariable risk prediction equations attempt to quantify an individual’s cardiovascular risk. Those borne from the Framingham Heart Study remain the most well-established and widely used. In February 2008, a new Framingham risk equation was published. We sought to determine the differences between the most commonly used Framingham equation from 1991 and the 2008 version through their application to a contemporary Australian population. METHODS AND RESULTS: The two risk equations were applied to 7329 individuals from the Australian Diabetes, Obesity and Lifestyle study. All individuals were aged 30–74 years and free of cardiovascular disease. Differences in median risk scores w..View full abstract
The authors wish to thank the AusDiab Steering Committee for providing data from the AusDiab study. The authors would also like to thank Sanofi-Aventis Australia for their contribution in partially funding this research. This project was funded by the Australian Government through the Australian Research Council and Sanofi-Aventis Australia.