Journal article

Intraoperative radiotherapy in women with early breast cancer treated by breast-conserving therapy

Boon H Chua, Michael A Henderson, Alvin D Milner

ANZ JOURNAL OF SURGERY | WILEY | Published : 2011

Abstract

BACKGROUND: Previous studies demonstrated the feasibility of intraoperative radiotherapy (IORT) to the primary tumour bed using a miniature electron beam driven X-ray source for early breast cancer. This study aimed to evaluate the feasibility of IORT as a tumour bed boost after whole breast irradiation (WBI) in breast conserving therapy. METHODS: This was a single-arm prospective trial for women with breast cancer measuring 90%. The protocol therapy would be considered unsuitable for further development if the completion rate was 15% of women who received IORT. RESULTS: Sixty patients were recruited for the study. IORT and WBI were delivered in 58 and 55 patients, respectively. Thus, the fe..

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