Journal article

Meat consumption and risk of primary hip and knee joint replacement due to osteoarthritis: a prospective cohort study

Yuanyuan Wang, Julie Anne Simpson, Anita Wluka, Dallas R English, Graham G Giles, Stephen Graves, Flavia M Cicuttini



BACKGROUND: There is emerging evidence for a beneficial effect of meat consumption on the musculoskeletal system. However, whether it affects the risk of knee and hip osteoarthritis is unknown. We performed a prospective cohort study to examine the relationship between meat consumption and risk of primary hip and knee replacement for osteoarthritis. METHODS: Eligible 35,331 participants were selected from the Melbourne Collaborative Cohort Study recruited during 1990-1994. Consumption of fresh red meat, processed meat, chicken, and fish was assessed using a food frequency questionnaire. Primary hip and knee replacement for osteoarthritis during 2001-2005 was determined by linking the cohort ..

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Awarded by National Health and Medical Research Council (NHMRC)

Awarded by NHMRC Public Health (Australia)

Funding Acknowledgements

The Melbourne Collaborative Cohort Study recruitment was funded by VicHealth and The Cancer Council of Victoria. This study was funded by a program grant from the National Health and Medical Research Council (NHMRC; 209057), capacity building grant (251533), and enabling grant (396414), and was further supported by infrastructure provided by The Cancer Council Victoria. Dr Wang is the recipient of NHMRC Public Health (Australia) Fellowship (NHMRC 465142). Dr Wluka is the recipient of NHMRC Career Development Award (NHMRC 545876). We would especially like to thank the data manager Lisa Ingerson and statistician Nicole Pratt from the Australian Orthopaedic Association National Joint Replacement Registry, and Ms Georgina Marr from The Cancer Council Victoria.